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Departamento de Santa Cruz Hotels for Your Next Holiday

Why Tourists Visit Departamento de Santa Cruz

  • • Relax on the sandy dunes at Lomas de Arena.
  • • Explore wildlife trails in Amboró National Park.
  • • Visit the historic Jesuit Mission Churches in San José de Chiquitos.
  • • Discover vibrant street markets in Santa Cruz de la Sierra’s city center.
  • • Tour the Biocentro Güembé for butterfly gardens and lagoons.

Departamento de Santa Cruz boasts over 350 accommodation options, ranging from family-run guesthouses to luxury resorts. Major hotel chains are concentrated in Santa Cruz de la Sierra, with 3-star hotels averaging $50-$80 per night and 5-star options costing $120-$250. Some newly opened hotels, such as Marriott Santa Cruz de la Sierra and Swissôtel Santa Cruz, stand out for their modern architecture and premium amenities, including infinity pools and wellness centers.

Known as Bolivia’s largest department and economic hub, Departamento de Santa Cruz is famous for its lush Amazonian plains, historical landmarks, and vibrant cultural scene.

Tourists flock to the region for its breathtaking attractions like the UNESCO-listed Jesuit Mission Churches, the stunning Amboró National Park, and the serene Lomas de Arena sand dunes.

The capital, Santa Cruz de la Sierra, offers a mix of colonial charm and modern amenities, serving as a perfect gateway to explore the region’s natural and cultural wonders.

Departamento de Santa Cruz Tips You Must Know

• Book your hotel 2-3 months in advance if traveling from May to September, the region’s peak tourist season.

• Consider staying in the Equipetrol district of Santa Cruz de la Sierra for easy access to restaurants and nightlife.

• Always check hotel transportation services, as some provide shuttles to Viru Viru International Airport.

• Pack for varied climates—light clothing for the city and warm, sturdy clothes for mountain or jungle tours.

• Opt for guided tours for safer, more efficient visits to remote areas like rainforest trails or mission routes.

Santa Cruz de la Sierra

Santa Cruz de la Sierra, the bustling capital of the department, blends modernity with tradition, featuring Plaza 24 de Septiembre as its cultural and social core. The city surprises visitors with its vibrant Equipetrol district, a hotspot for dining and nightlife. Nearby, the Zoológico Municipal Noel Kempff is home to rare Amazonian species, offering an urban escape to nature.

Discover the wide range of hotels in Santa Cruz de la Sierra to complement your exploration of this dynamic city.

San José de Chiquitos

San José de Chiquitos, a UNESCO World Heritage site, charms with the Jesuit Mission Church, an architectural wonder dating back to the 18th century. The Santa Cruz Highlands nearby reveal stunning landscapes, perfect for hiking and birdwatching. This serene town stands out for its unique blend of colonial and indigenous influences.

Find tranquil hotels in San José de Chiquitos for easy access to its historical and natural wonders.

Samaipata

Samaipata captivates travelers with its famous El Fuerte, a pre-Columbian ruin and UNESCO site that sits atop tranquil mountains. The region’s cool climate and vineyards invite wine enthusiasts while its vibrant Saturday markets offer rich local culture. Adventurers use the city as a base for exploring Amboró National Park.

Check out cozy and scenic hotels in Samaipata to enjoy its blend of history and nature.

Puerto Suárez

Puerto Suárez, lying near the Brazilian border, invites visitors to the Pantanal wetlands, one of the most biodiverse ecosystems in the world. This gateway city is perfect for eco-tourism, boat tours, and spotting unique wildlife like capybaras and caimans. Its fascinating location offers insights into cross-border cultures and trade.

Explore hotels in Puerto Suárez to enjoy a comfortable stay near stunning wetlands and wildlife.

Montero

Montero, a rapidly growing urban hub north of Santa Cruz de la Sierra, buzzes with agricultural prosperity. The dynamic Mercado Abasto showcases the region’s fresh produce and vibrant local life. Beautiful countryside nearby offers opportunities for off-the-beaten-path exploration and rural tourism experiences.

Choose from various hotels in Montero for a mix of city life and countryside adventure.

Central Hotels that Keep You Close to the Action

Find more central Central hotels in Santa Cruz de la Sierra that put you right where the action is.

Hotel Name
Description
#
Price per night

La Siesta Hotel

City Center

  • Plaza 24 de Septiembre (0.5 km)
  • Museo de Arte Contemporáneo (1 km)
  • Cathedral of Santa Cruz (0.6 km)

Once a colonial-style residence, this hotel preserves its charming architecture while featuring a refreshing central courtyard.

  • Location in downtown Santa Cruz

  • Colonial ambiance

  • Affordable rates

$40-$60/night

Cosmopolitano Hotel Boutique

City Center

  • Arenal Park (0.8 km)
  • Plaza 24 de Septiembre (0.4 km)
  • City Market (1 km)

This stylish boutique escape is known for its vibrant art collection that decorates every corner of the property.

  • Trendy decor

  • Excellent rooftop pool

  • Personalized service

$90-$130/night

Hotel Camino Real

Urubó

  • Las Palmas Golf Club (3 km)
  • Ventura Mall (2.5 km)
  • Biocentro Güembé (6 km)

This modern hotel is famous for its lagoon pool and spa, offering a resort feel right in the city.

  • Excellent wellness amenities

  • Spacious rooms

  • Famous for its pool

$120-$180/night

Luxury Hotels with Unforgettable Experiences

Explore the finest Luxury hotels in Santa Cruz de la Sierra for a truly indulgent stay.

Hotel Name
Description
#
Price per night

Chairu Eco Hotel

Equipetrol

  • Ventura Mall (1 km)
  • Plaza 24 de Septiembre (6 km)
  • Aqualand (10 km)

This eco-friendly luxury hotel integrates seamlessly with nature, featuring locally sourced materials and green-energy solutions.

  • Eco-conscious design

  • Tranquil setting

  • Close to entertainment areas

$150-$220/night

Senses Hotel Boutique Plaza

City Center

  • Plaza 24 de Septiembre (0 km)
  • Cathedral of Santa Cruz (0.1 km)
  • Arenal Park (0.8 km)

Located right on Plaza 24 de Septiembre, this hotel boasts panoramic views of the city’s historic center from its rooftop bar.

  • Prime location

  • Rooftop bar

  • Elegant interiors

$100-$160/night

Sun Hotel

Viru Viru

  • Viru Viru International Airport (3 km)
  • Biocentro Güembé (8 km)
  • Ventura Mall (10 km)

Located just minutes from the airport, this luxury hotel is a haven for travelers with its sprawling outdoor pool and lush garden.

  • Close to the airport

  • Large swimming pool

  • Ideal for business travelers

$130-$200/night

Boutique Hotels Full of Personality

Check out more unique Boutique hotels in Santa Cruz de la Sierra with unmatched style and charm.

Hotel Name
Description
#
Price per night

Los Tajibos, Santa Cruz De La Sierra, A Tribute Portfolio Hotel

Equipetrol

  • Ventura Mall (1 km)
  • Plaza 24 de Septiembre (4 km)
  • Biocentro Güembé (9 km)

This renowned boutique hotel features sprawling gardens and a poolside ambiance for both relaxation and business gatherings.

  • Elegant gardens

  • Excellent dining options

  • Ideal for events

$170-$250/night

Alfonsina Hotel Boutique

Equipetrol

  • Plaza 24 de Septiembre (5 km)
  • Ventura Mall (1.2 km)
  • Aqualand (12 km)

This hidden-gem hotel is a favorite for its intimate ambiance and curated collection of Bolivian handicrafts.

  • Artisan decorations

  • Private setting

  • Great for couples

$120-$180/night

Hotel Senses Centro

City Center

  • Plaza 24 de Septiembre (0.4 km)
  • Cathedral of Santa Cruz (0.5 km)
  • Arenal Park (0.2 km)

This hotel captures attention with its innovative room layouts and focus on personalized, high-tech guest experiences.

  • Next-gen room design

  • Tech-focused amenities

  • Close to historical sites

$100-$140/night

Family-Friendly Hotels for All Ages

Discover more welcoming Family Friendly hotels in Santa Cruz de la Sierra for the perfect family holiday.

Hotel Name
Description
#
Price per night

Hotel Plaza Center

City Center

  • Plaza 24 de Septiembre (0.5 km)
  • Arenal Park (0.6 km)
  • City Museum (1 km)

This hotel caters to families with its spacious suites, on-site playground, and kids’ menu at the restaurant.

  • Family-oriented amenities

  • Great dining options

  • Central location

$80-$130/night

Yvy Casa Hotel

Equipetrol

  • Ventura Mall (0.8 km)
  • Plaza 24 de Septiembre (4.5 km)
  • Biocentro Güembé (8.5 km)

This boutique-style family hotel is famous for its large treehouse play area and cozy communal spaces.

  • Unique play areas

  • Homey atmosphere

  • Great location for families

$100-$150/night

Buganvillas Hotel Suites

Los Tusequis

  • Plaza 24 de Septiembre (5 km)
  • Las Brisas Mall (1 km)
  • El Cristo Monument (3.5 km)

Families love this hotel for its villa-style suites and activity-packed garden, including soccer fields and outdoor pools.

  • Spacious suites

  • Outdoor sports facilities

  • Kid-friendly pools

$90-$160/night

Hotels with Indoor Pools that Wow

Explore more relaxing Hotels with indoor pool in Santa Cruz de la Sierra with stylish pools for unwinding year-round.

Hotel Name
Description
#
Price per night

Departamentos En Edificio Acrebol Santa Cruz

City Center

  • Plaza 24 de Septiembre (2 km)
  • Arenal Park (1.8 km)
  • Ventura Mall (2.5 km)

This serviced apartment offers an indoor pool with fantastic city views—a rarity for urban accommodations in Santa Cruz.

  • Indoor pool

  • Fully equipped apartment

  • Great for long stays

$70-$100/night

Apartamento Moderno Equipetrol: Cinema, Pool & Gym with Free Parking

Equipetrol

  • Ventura Mall (0.5 km)
  • Plaza 24 de Septiembre (4 km)
  • Biocentro Güembé (9 km)

Perfect for tech-lovers, this rental features a private cinema room along with an indoor pool and gym facilities.

  • Private cinema

  • Indoor pool

  • Great area amenities

$60-$90/night

Apartamento Moderno, Delicado Y Confortable

City Center

  • Arenal Park (1 km)
  • Plaza 24 de Septiembre (2.2 km)
  • Cathedral of Santa Cruz (2.4 km)

This sleek Airbnb-style rental boasts an indoor pool within a luxury complex, perfect for rainy-day relaxation.

  • Indoor pool

  • Clean, modern design

  • Close to attractions

$50-$80/night

Frequently asked question

What are the best hotels located near Plaza 24 de Septiembre in Santa Cruz?

Many hotels like Los Tajibos and Senses Boutique Hotel offer walking distance access to Plaza 24 de Septiembre, great views, and upscale amenities.

Are there family-friendly hotels in Departamento de Santa Cruz?

Yes, hotels such as Radisson Hotel Santa Cruz provide family amenities like pools, spacious rooms, and on-site dining for kids.

What are the typical prices for boutique hotels in Santa Cruz?

Boutique hotels usually range from $70 to $150 per night, with options like Marriott Santa Cruz showcasing stylish decor and modern amenities.

Are there budget-friendly accommodations near Biocentro Güembé in Santa Cruz?

Yes, affordable hotels like House Inn Hotel have reasonable prices starting around $40 per night and are conveniently located near Biocentro Güembé.

Which hotels offer easy access to Viru Viru International Airport?

Camino Real Hotel and Sun Hotel are top choices, located less than 20 minutes from Viru Viru International Airport with shuttle options available.

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